Extracellular vesicles (EVs ) play a vital role in brain tumour stem cell (BTSC) biology by mediating inter-cellular communication within the tumour microenvironment. They transfer oncogenic proteins, RNAs, and signaling molecules, influencing tumour growth, therapy resistance, and metastasis. Understanding EVs offers new opportunities for developing targeted therapies and reliable biomarkers for early detection and monitoring of brain tumours. Introduction: Brain tumour stem cells (BTSCs) are a subpopulation within brain tumours, such as glioblastoma, that drive tumour initiation, progression, recurrence, and therapy resistance. Understanding the mechanisms that maintain BTSCs is crucial for developing more effective treatments. Role of Extracellular Vesicles (EVs): Extracellular vesicles — including exosomes and microvesicles — are nano-sized, membrane-bound particles secreted by cells to transport bioactive molecules like proteins, lipids, mRNAs, and microRNAs. In brain tum...
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