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Thyroid Dysfunction from Treatments for Solid Organ Cancers

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  1. Meaning (Definition) Thyroid dysfunction from treatments for solid organ cancers refers to abnormal changes in thyroid gland function induced by cancer therapies , including chemotherapy, targeted therapy, immunotherapy, radiation therapy, and combination regimens. These abnormalities may manifest as: Hypothyroidism Hyperthyroidism Thyroiditis Subclinical thyroid disease Rarely, structural thyroid damage Rather than arising from primary thyroid disease, these conditions occur secondary to anticancer treatment–related effects on thyroid tissue, immune regulation, or hormonal signaling pathways . 2. Introduction The rapid expansion of modern oncologic therapies has markedly improved survival in patients with solid organ malignancies such as lung, breast, kidney, liver, colorectal, melanoma, and head-and-neck cancers. However, many of these therapies unintentionally disrupt endocrine homeostasis. Among endocrine complications, thyroid dysfunction is one of t...
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Quantitative knowledge presentation models of traditional Chinese medicine (TCM): A review

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  Meaning Quantitative Knowledge Presentation Models of Traditional Chinese Medicine (TCM) refer to computational and mathematical frameworks designed to transform traditional qualitative, experience-based TCM knowledge into measurable, structured, and interpretable representations . These models aim to encode complex TCM concepts—such as syndromes (Zheng), herbal properties, meridians, and therapeutic relationships—into numerical, graphical, or algorithmic formats that enable statistical analysis, machine learning, and data-driven reasoning. In essence, these models serve as a bridge between ancient medical wisdom and modern biomedical informatics, allowing TCM knowledge to be stored, analyzed, shared, and validated using quantitative scientific methods. Introduction Traditional Chinese Medicine has evolved over thousands of years through empirical observation, philosophical reasoning, and clinical practice. While TCM is rich in theoretical depth and holistic perspectives, muc...
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40th Edition of Best Paper Awards 27-28th February 2026 | Singapore

  40th Edition of Best Paper Awards 27-28th February 2026 | Singapore International Research Excellence and Best Paper Awards Website: bestpaperawards.com Nomination Link: https://bestpaperawards.com/award-nom... For Enquiries: contact@bestpaperawards.com #Scifax #Beststpaperawards #Researcherawards #Mostcitedarticleaward #Researcharticleaward #AcademicAwards #ResearchInnovation #ScientificAchievement #TopResearch #AIResearch #STEMExcellence #PublishingSuccess #AwardWinningResearch #GlobalRecognition #InnovationAward #Scholarship #AcademicSuccess #ScienceAwards #TechBreakthrough #PeerReviewed #ScientificImpact #ResearchFunding #ExcellenceInResearch Get Connected Here: ================== Youtube: / @researchpapertv5756 Twitter : twitter.com/bestpaperaward Pinterest : in.pinterest.com/bestpaperaward Linkedin : www.linkedin.com/in/esha-gupta-18b2b4245 Instagram: www.instagram.com/eshagupta__2022/ Blogger: bestpaperaward.blogspot.com/
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Physical exercise, cognition, and brain health in aging

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  Meaning Physical exercise, cognition, and brain health in aging refers to the interconnected relationship between regular bodily movement and its influence on mental processes—such as memory, attention, learning, and executive function—as well as the structural and functional integrity of the brain across the lifespan. As individuals age, natural biological changes occur in neural networks, neurotransmitter systems, and cerebral blood flow, which can lead to gradual cognitive decline. Physical exercise serves as a powerful, non-pharmacological intervention that can slow, prevent, or even partially reverse many of these age-related changes. This concept emphasizes that movement is not only beneficial for muscles and cardiovascular health but also plays a critical role in maintaining cognitive vitality and neurological resilience. Introduction Aging is accompanied by a progressive decline in many physiological systems, and the brain is no exception. Older adults frequently expe...
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Waste Clearance Shapes Aging Brain Health

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  Meaning Waste clearance in the brain refers to the biological processes responsible for removing metabolic by-products, misfolded proteins, damaged cellular components, and toxins that accumulate during normal neuronal activity. Unlike other organs, the brain lacks conventional lymphatic vessels within its parenchyma and instead relies on specialized systems such as the glymphatic pathway , cerebrospinal fluid (CSF) circulation, blood– brain barrier (BBB) transport mechanisms, and cellular degradation pathways like autophagy and proteasomal systems. These interconnected processes collectively maintain neural homeostasis. As the brain ages, efficiency of waste clearance declines, leading to accumulation of neurotoxic substances that contribute to cognitive decline and neurodegenerative diseases. Introduction Aging is accompanied by progressive changes in brain structure and function, including reduced synaptic plasticity, neuronal loss, and altered neurotransmission. A central ...
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